Bino John

Address:
University of Pittsburgh School of Medicine
Member, University of Pittsburgh Cancer Institute
3080 Biomedical Science Tower 3
3501 Fifth Avenue
Pittsburgh, PA 15213,USA

Phone: (412); 648-8607
Email: john@johnlab.org
Homepage: Visit

Background:

When and where you received your PhD
2003, The Rockefeller University, New York, NY 10021

Where you did your postdoc
Memorial Sloan-Kettering Cancer Centre

Research:

The broad objective of our research is to help cure human diseases by developing bioinformatics/computational and experimental methods to study gene functions. Recent studies link non-protein-coding RNAs to cancer and other diseases. Noncoding RNAs such as microRNAs are thought to post-transcriptionally regulate a large number of human genes. The research on non-coding RNAs is likely to provide new diagnostic and prognostic markers and eventually therapeutic targets for the treatment of human diseases. We also aim to develop methods to aid computer aided drug design efforts. Our research strategy is to apply bioinformatics/computational methods to formulate reasonable hypotheses about interesting biological problems and subsequently conduct experiments to test them. Current projects in our laboratory include but are not limited to:
1. Discovering new non-protein-coding RNAs such as microRNAs
2. Identifying functions of specific disease (eg, viruses and cancer); associated non-coding RNAs
3. Identifying novel gene regulatory networks in cancer and other diseases.
4. Developing new methods to determine protein/rna structure